Anti-Aging Potential of Boosting NAD
“Rewinding the Clock on Aging Blood Vessels“
Dr David Sinclair
Video by Harvard Medical School
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Therapeutic Potential of Boosting NAD in Aging & Age-Related Diseases
Abstract from: sciencedirect.com
- Nicotinamide adenine dinucleotide NAD is an essential cofactor in all living cells that is involved in fundamental biological processes.
- NAD depletion has been associated with hallmarks of aging and may underlie a wide-range of age-related diseases, such as metabolic disorders, cancer and neurodegenerative diseases.
- Emerging evidence implicates that elevation of NAD levels may slow or even reverse the aspects of aging and also delay the progression of age-related diseases.
- Boosting NAD levels may emerge as a promising therapeutic strategy to counter aging-associated pathologies and/or accelerated aging.
Learn How to Increase NAD Levels Naturally
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David Sinclair, Ph.D. “Lifespan: Why We Age–and Why We Don’t Have To“
David A. Sinclair, Ph.D. is a Professor in the Department of Genetics at Harvard Medical School and co-Director of the Paul F. Glenn Center for the Biological Mechanisms of Aging. He is best known for his work on understanding why we age and how to slow its effects. He obtained his Ph.D. in Molecular Genetics at the University of New South Wales, Sydney in 1995. He worked as a postdoctoral researcher at M.I.T. with Dr. Leonard Guarente where he co discovered a cause of aging for yeast as well as the role of Sir2 in epigenetic changes driven by genome instability.
In 1999 he was recruited to Harvard Medical School where his laboratory’s research has focused primarily on understanding the role of sirtuins in disease and aging, with associated interests in chromatin, energy metabolism, mitochondria, learning and memory, neurodegeneration, and cancer. He has also contributed to the understanding of how sirtuins are modulated by endogenous molecules and pharmacological agents such as resveratrol.
Dr. Sinclair is co-founder of several biotechnology companies (Sirtris, Ovascience, Genocea, Cohbar, MetroBiotech, ArcBio, Liberty Biosecurity) and is on the boards of several others. He is also co-founder and co-chief editor of the journal Aging. His work is featured in five books, two documentary movies, 60 Minutes, Morgan Freeman’s “Through the Wormhole” and other media. He is an inventor on 35 patents and has received more than 25 awards and honors. Learn more about Rewinding the Clock on Aging Blood Vessels and anti aging NAD.
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